6 comments

  • flextheruler 47 minutes ago
    8 people as the entire control group... yeah I'd say "may" is the operative word in the title. My takeaway from long covid is that it's probably as severe as the much more deadly pandemic of the Spanish Flu. Considering there's now a newfound interest in "long flu", I think a spotlight has now been placed on the impact of severe respiratory illness. Whether that illness be covid or one of the any other respiratory illnesses.
    • jambalaya8 34 minutes ago
      Yeah, twelve patients and eight in the control group isn't really a study.
      • thenerdhead 5 minutes ago
        is a small proof of concept study not a study anymore? gastric biopsies aren’t exactly easy to obtain at scale.
    • thenerdhead 30 minutes ago
      severity is only one factor in developing long covid.

      https://www.thelancet.com/journals/laninf/article/PIIS1473-3...

    • naturalmovement 29 minutes ago
      Funny that reactive arthritis has been around for decades but no one dares call it "long chlamydia" I guess it doesn't sell YouTube clicks as well.
    • jMyles 32 minutes ago
      It's strange that the phrase "long covid" has suddenly jumped into our lexicon, when there has been a similar tiny minority of patients reporting similar symptoms from the other coronaviruses for decades now.

      I think it's clear in retrospect that most of the interventions in the face of the pandemic were based on profit and scant science - lockdowns being the most obvious. But increased study and awareness of post-infection syndromes without the kind of high-brow dismissal that these patients have received up until now... well, that's certainly an acceptable silver lining.

  • kranke155 1 hour ago
    hopefully we will get somewhere with these studies. The lack of solid research on a disease that affects millions (likely a good percentage undiagnosed) is really tough for patients - and myself really, as I've found i likely suffer from this.

    Finding out about autonomic dysfunction and small fiber neuropathy as I researched my own fatigue and finding out I likely have this has been very challenging.

    • naturalmovement 6 minutes ago
      > as I researched my own fatigue and finding out I likely have this

      Please don't do this. It's the medical equivalent of copy/pasting shit you don't understand from Stack Overflow.

      Go see a doctor who has a degree and training.

    • zx8080 1 hour ago
      It's probably more profitable to treat symptoms.
      • jambalaya8 37 minutes ago
        Hard to treat symptoms with immunological conditions. I mean, there are vitamins and supplements, but noone is gonna generally hand out economy-sized bottles of controlled substances for exhaustion, etc.

        These sorts of conditions are systemic, and the causes and ways of dealing with the accompanying syndromes are probably always going to be different from individual to individual (well, likely the exact physiological causes anyway).

      • jmye 52 minutes ago
        [dead]
  • peab 49 minutes ago
    i noticed a thing with headlines like these: "x may cause y". Whenever it's "may" or "might", it's almost always meaningless
    • naturalmovement 42 minutes ago
      Not to worry, there's three dozen commenters on the way to attest long COVID is definitely the source of their many nonspecific ailments that could easily be ascribed to various other illnesses.
      • jambalaya8 32 minutes ago
        Problem with those conditions and long COVID and CFS are generally similar: No really reliable guaranteed test for most of them, just a series of symptomatic diagnoses and years of ruling out conditions. No offense, but while some people might be full of crap, you sound really insensitive.
        • naturalmovement 20 minutes ago
          If you suppose it's all malarkey and conjecture, what is the problem?

          When your doctor says that you're wrong, do you accept his advice or tell him he should be more like Dale Carnegie?

          • jambalaya8 10 minutes ago
            Most logical, rational adults would seek a second opinion, at least in places where those are available; they usually are. Interesting that I said 'some people' and you generalised.

            FWIW, if my doctor were unfriendly enough, though, I might do that also.

    • thenerdhead 36 minutes ago
      small study yes, meaningless no
    • shiggydump 47 minutes ago
      Only the Sith deal in absolutes.
  • jph00 59 minutes ago
    Wow mucosal innervation was around half in long covid patients - that's super worrying and would have nasty symptoms in practice.

    The findings also support the hypothesis that SARS-CoV-2 may cause structural nerve damage, which is perhaps the even bigger worry. :(

    • RandomTisk 22 minutes ago
      What kind of symptoms? I have insane stomach issues since early 2021 that only this year started to largely subside.
  • remarkEon 40 minutes ago
    Is there a test for long covid?
    • nradov 29 minutes ago
      There's no such thing as "long COVID" specifically. Any serious viral infection has the potential to cause sequalae in susceptible patients for reasons that are still not well understood. Some of those are detectible in lab tests to an extent but there's no single clear diagnostic test.
      • thenerdhead 20 minutes ago
        they are pretty well understood now with growing evidence of viral persistence in the gut and immune cells, and immune dysfunction causing autoantibodies.

        they are also distinct from other conditions like ME/CFS or other sequelae although they may share overlapping symptoms. A lot of research is going into different PAIS post acute infection syndromes

    • thenerdhead 35 minutes ago
      not quite. A grab bag of biomarkers being validated in research labs across the USA though
    • LorenPechtel 14 minutes ago
      Think of AIDS before the immune system dysfunction was found. That's where we are with Long Covid. One cause, a myriad of apparently unrelated effects--that's not how biology tends to work. Rather, there's something deeper we haven't found. And we certainly can't test for what we haven't found.
  • vismit2000 21 minutes ago
    Physics Girl Dianna Cowern Living With Long COVID: https://en.wikipedia.org/wiki/Dianna_Cowern